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Microvascular complications and its predictors among type 2 diabetes mellitus patients at Dessie town hospitals, Ethiopia
BACKGROUND: Diabetes mellitus is a serious metabolic disorder which becomes common in middle and low incomes countries since few decades. Microvascular complications include retinopathy, neuropathy and nephropathy all of which can lead to disability, dependency, accelerate their morbidity, and morta...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369723/ https://www.ncbi.nlm.nih.gov/pubmed/34404465 http://dx.doi.org/10.1186/s13098-021-00704-w |
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author | Seid, Mohammed Abdu Akalu, Yonas Gela, Yibeltal Yismaw Belsti, Yitayeh Diress, Mengistie Fekadu, Sofonias Addis Dagnew, Baye Getnet, Mihret |
author_facet | Seid, Mohammed Abdu Akalu, Yonas Gela, Yibeltal Yismaw Belsti, Yitayeh Diress, Mengistie Fekadu, Sofonias Addis Dagnew, Baye Getnet, Mihret |
author_sort | Seid, Mohammed Abdu |
collection | PubMed |
description | BACKGROUND: Diabetes mellitus is a serious metabolic disorder which becomes common in middle and low incomes countries since few decades. Microvascular complications include retinopathy, neuropathy and nephropathy all of which can lead to disability, dependency, accelerate their morbidity, and mortality. In Ethiopia, there is paucity data regarding this topic. Hence, this study aimed to assess prevalence of microvascular complications and its predictors among type 2 diabetes mellitus patients. METHODS: Cross-sectional study was conducted from February to March 2020 at Dessie town hospitals. We used simple random sampling to recruit study participants and pre-tested interviewer administered questionnaire to collect the data. Data was entered into Epi-Data 3.1 and exported to SPSS-23 for analysis. Binary logistic regression was done to select potential variables to be adjusted at p ≤ 0.25. After running multivariable regression, variables with a p-value ≤ 0.05 were declared as statistically significant. RESULTS: Three hundred and thirty-five type 2 DM patients participated in the study, of which 54.6% were males. One hundred and twenty-seven [37.9% (95% CI 32.5%–43.3%)] of diabetes mellitus had at least one microvascular complications. These were retinopathy 24.8%, nephropathy 16.1%, and neuropathy 8.1%. Age 60–87 years (AOR = 2.76, 95% CI 1.02–7.46), duration of diabetes > 5 years (AOR = 4.09, 95% CI 2.40–6.96), mellitus and co-morbid hypertension (AOR = 3.52, 95% CI 2.09–5.95), were statistically significant. CONCLUSIONS: In this study, diabetic microvascular complications are prevalent. Increasing the age of participants, longer duration of diabetes mellitus and co-morbid hypertension were independent predictors. Health workers should give emphasis for diabetes mellitus through early screening and health education, abrupt medication for aged patients with long duration of diabetes mellitus, and hypertension, and also early detection and management of microvascular complication. |
format | Online Article Text |
id | pubmed-8369723 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-83697232021-08-18 Microvascular complications and its predictors among type 2 diabetes mellitus patients at Dessie town hospitals, Ethiopia Seid, Mohammed Abdu Akalu, Yonas Gela, Yibeltal Yismaw Belsti, Yitayeh Diress, Mengistie Fekadu, Sofonias Addis Dagnew, Baye Getnet, Mihret Diabetol Metab Syndr Research BACKGROUND: Diabetes mellitus is a serious metabolic disorder which becomes common in middle and low incomes countries since few decades. Microvascular complications include retinopathy, neuropathy and nephropathy all of which can lead to disability, dependency, accelerate their morbidity, and mortality. In Ethiopia, there is paucity data regarding this topic. Hence, this study aimed to assess prevalence of microvascular complications and its predictors among type 2 diabetes mellitus patients. METHODS: Cross-sectional study was conducted from February to March 2020 at Dessie town hospitals. We used simple random sampling to recruit study participants and pre-tested interviewer administered questionnaire to collect the data. Data was entered into Epi-Data 3.1 and exported to SPSS-23 for analysis. Binary logistic regression was done to select potential variables to be adjusted at p ≤ 0.25. After running multivariable regression, variables with a p-value ≤ 0.05 were declared as statistically significant. RESULTS: Three hundred and thirty-five type 2 DM patients participated in the study, of which 54.6% were males. One hundred and twenty-seven [37.9% (95% CI 32.5%–43.3%)] of diabetes mellitus had at least one microvascular complications. These were retinopathy 24.8%, nephropathy 16.1%, and neuropathy 8.1%. Age 60–87 years (AOR = 2.76, 95% CI 1.02–7.46), duration of diabetes > 5 years (AOR = 4.09, 95% CI 2.40–6.96), mellitus and co-morbid hypertension (AOR = 3.52, 95% CI 2.09–5.95), were statistically significant. CONCLUSIONS: In this study, diabetic microvascular complications are prevalent. Increasing the age of participants, longer duration of diabetes mellitus and co-morbid hypertension were independent predictors. Health workers should give emphasis for diabetes mellitus through early screening and health education, abrupt medication for aged patients with long duration of diabetes mellitus, and hypertension, and also early detection and management of microvascular complication. BioMed Central 2021-08-17 /pmc/articles/PMC8369723/ /pubmed/34404465 http://dx.doi.org/10.1186/s13098-021-00704-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Seid, Mohammed Abdu Akalu, Yonas Gela, Yibeltal Yismaw Belsti, Yitayeh Diress, Mengistie Fekadu, Sofonias Addis Dagnew, Baye Getnet, Mihret Microvascular complications and its predictors among type 2 diabetes mellitus patients at Dessie town hospitals, Ethiopia |
title | Microvascular complications and its predictors among type 2 diabetes mellitus patients at Dessie town hospitals, Ethiopia |
title_full | Microvascular complications and its predictors among type 2 diabetes mellitus patients at Dessie town hospitals, Ethiopia |
title_fullStr | Microvascular complications and its predictors among type 2 diabetes mellitus patients at Dessie town hospitals, Ethiopia |
title_full_unstemmed | Microvascular complications and its predictors among type 2 diabetes mellitus patients at Dessie town hospitals, Ethiopia |
title_short | Microvascular complications and its predictors among type 2 diabetes mellitus patients at Dessie town hospitals, Ethiopia |
title_sort | microvascular complications and its predictors among type 2 diabetes mellitus patients at dessie town hospitals, ethiopia |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369723/ https://www.ncbi.nlm.nih.gov/pubmed/34404465 http://dx.doi.org/10.1186/s13098-021-00704-w |
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