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Longest reported case of symptomatic COVID-19 reporting positive for over 230 days in an immunocompromised patient in the United States

Coronavirus 2019 (COVID-19) pneumonia was first noted in Wuhan, China. Since the start of the pandemic, there have been millions of cases diagnosed. The average time from onset of symptoms to testing negative SARS-CoV-2 via reverse transcription polymerase chain reaction is roughly 25 days. In patie...

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Autores principales: Chaudhry, Bilal, Didenko, Lidiya, Chaudhry, Maaria, Malek, Andrew, Alekseyev, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369853/
https://www.ncbi.nlm.nih.gov/pubmed/34413976
http://dx.doi.org/10.1177/2050313X211040028
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author Chaudhry, Bilal
Didenko, Lidiya
Chaudhry, Maaria
Malek, Andrew
Alekseyev, Kirill
author_facet Chaudhry, Bilal
Didenko, Lidiya
Chaudhry, Maaria
Malek, Andrew
Alekseyev, Kirill
author_sort Chaudhry, Bilal
collection PubMed
description Coronavirus 2019 (COVID-19) pneumonia was first noted in Wuhan, China. Since the start of the pandemic, there have been millions of cases diagnosed. The average time from onset of symptoms to testing negative SARS-CoV-2 via reverse transcription polymerase chain reaction is roughly 25 days. In patients who continually test positive for COVID-19, it is essential to determine precisely which risk factors contribute to the increase in viral shedding duration. We present a case about a 62-year-old man who has persistently tested positive for COVID-19 for more than 230 days. We followed his treatment course, in which he had been hospitalized multiple times since the onset of symptoms back in April 2020. We have determined that patients with immunosuppression, especially those taking corticosteroids, are at increased risk of prolonged viral shedding. It is essential to continually monitor these immunocompromised patients as they required a greater time period in order to have an appropriate immune response in which antibodies are created.
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spelling pubmed-83698532021-08-18 Longest reported case of symptomatic COVID-19 reporting positive for over 230 days in an immunocompromised patient in the United States Chaudhry, Bilal Didenko, Lidiya Chaudhry, Maaria Malek, Andrew Alekseyev, Kirill SAGE Open Med Case Rep Case Report Coronavirus 2019 (COVID-19) pneumonia was first noted in Wuhan, China. Since the start of the pandemic, there have been millions of cases diagnosed. The average time from onset of symptoms to testing negative SARS-CoV-2 via reverse transcription polymerase chain reaction is roughly 25 days. In patients who continually test positive for COVID-19, it is essential to determine precisely which risk factors contribute to the increase in viral shedding duration. We present a case about a 62-year-old man who has persistently tested positive for COVID-19 for more than 230 days. We followed his treatment course, in which he had been hospitalized multiple times since the onset of symptoms back in April 2020. We have determined that patients with immunosuppression, especially those taking corticosteroids, are at increased risk of prolonged viral shedding. It is essential to continually monitor these immunocompromised patients as they required a greater time period in order to have an appropriate immune response in which antibodies are created. SAGE Publications 2021-08-13 /pmc/articles/PMC8369853/ /pubmed/34413976 http://dx.doi.org/10.1177/2050313X211040028 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Chaudhry, Bilal
Didenko, Lidiya
Chaudhry, Maaria
Malek, Andrew
Alekseyev, Kirill
Longest reported case of symptomatic COVID-19 reporting positive for over 230 days in an immunocompromised patient in the United States
title Longest reported case of symptomatic COVID-19 reporting positive for over 230 days in an immunocompromised patient in the United States
title_full Longest reported case of symptomatic COVID-19 reporting positive for over 230 days in an immunocompromised patient in the United States
title_fullStr Longest reported case of symptomatic COVID-19 reporting positive for over 230 days in an immunocompromised patient in the United States
title_full_unstemmed Longest reported case of symptomatic COVID-19 reporting positive for over 230 days in an immunocompromised patient in the United States
title_short Longest reported case of symptomatic COVID-19 reporting positive for over 230 days in an immunocompromised patient in the United States
title_sort longest reported case of symptomatic covid-19 reporting positive for over 230 days in an immunocompromised patient in the united states
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369853/
https://www.ncbi.nlm.nih.gov/pubmed/34413976
http://dx.doi.org/10.1177/2050313X211040028
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