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Bivalirudin Attenuates Thrombin-Induced Endothelial Hyperpermeability via S1P/S1PR2 Category: Original Articles

Aims: To explore the role of the Sphingosine 1-Phosphate (S1P)/Receptor2 (S1PR2) pathway in thrombin-induced hyperpermeability (TIP) and to test whether bivalirudin can reverse TIP via the S1P-S1PRs pathway. Methods and Results: Using western blot, we demonstrated that Human umbilical vein endotheli...

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Detalles Bibliográficos
Autores principales:	Ye, Haowen, Zhang, Yizhi, Huang, Yihui, Li, Biao, Cao, Ruhao, Dai, Libing, Huang, Bin, Tian, Pingge, Li, Li, Han, Yaling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369898/ https://www.ncbi.nlm.nih.gov/pubmed/34413778 http://dx.doi.org/10.3389/fphar.2021.721200

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