DNA Methylation Markers for Detection of Cholangiocarcinoma: Discovery, Validation, and Clinical Testing in Biliary Brushings and Plasma

Cholangiocarcinoma (CCA) has poor prognosis due to late‐stage, symptomatic presentation. Altered DNA methylation markers may improve diagnosis of CCA. Reduced‐representation bisulfite sequencing was performed on DNA extracted from frozen CCA tissues and matched to adjacent benign biliary epithelia o...

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Detalles Bibliográficos
Autores principales: Yang, Ju Dong, Ghoz, Hassan, Aboelsoud, Mohammed M., Taylor, William R., Yab, Tracy C., Berger, Calise K., Cao, Xiaoming, Foote, Patrick H., Giama, Nasra H., Barr Fritcher, Emily G., Mahoney, Douglas W., Moser, Catherine D., Smyrk, Thomas C., Kipp, Benjamin R., Gores, Gregory J., Roberts, Lewis R., Kisiel, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369938/
https://www.ncbi.nlm.nih.gov/pubmed/34430788
http://dx.doi.org/10.1002/hep4.1730

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