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Cooperation Between Systemic IgG1 and Mucosal Dimeric IgA2 Monoclonal Anti-HIV Env Antibodies: Passive Immunization Protects Indian Rhesus Macaques Against Mucosal SHIV Challenges

Understanding the interplay between systemic and mucosal anti-HIV antibodies can provide important insights to develop new prevention strategies. We used passive immunization via systemic and/or mucosal routes to establish cause-and-effect between well-characterized monoclonal antibodies and protect...

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Detalles Bibliográficos
Autores principales: Gong, Siqi, Lakhashe, Samir K., Hariraju, Dinesh, Scinto, Hanna, Lanzavecchia, Antonio, Cameroni, Elisabetta, Corti, Davide, Ratcliffe, Sarah J., Rogers, Kenneth A., Xiao, Peng, Fontenot, Jane, Villinger, François, Ruprecht, Ruth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370093/
https://www.ncbi.nlm.nih.gov/pubmed/34413855
http://dx.doi.org/10.3389/fimmu.2021.705592