Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions

Nano-Pulse Stimulation (NPS) therapy applies nanosecond pulsed electric fields to cells and tissues. It is a nonthermal modality that uses ultrashort pulses of electrical energy in the nanosecond domain. The cellular response to this therapy can be quite varied depending on the number of pulses appl...

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Autor principal: Nuccitelli, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370293/
https://www.ncbi.nlm.nih.gov/pubmed/34471826
http://dx.doi.org/10.1089/bioe.2019.0027
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author Nuccitelli, Richard
author_facet Nuccitelli, Richard
author_sort Nuccitelli, Richard
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description Nano-Pulse Stimulation (NPS) therapy applies nanosecond pulsed electric fields to cells and tissues. It is a nonthermal modality that uses ultrashort pulses of electrical energy in the nanosecond domain. The cellular response to this therapy can be quite varied depending on the number of pulses applied and the total energy delivered. Reviewed in this study are some clinical trial data describing the effects of NPS therapy on normal skin as well as three different skin lesions as part of the first commercial application of this technology. NPS therapy has been found to clear seborrheic keratosis lesions with an 82% efficacy and sebaceous gland hyperplasia with a 99.5% efficacy. Pilot studies on warts indicated that 60% of the NPS-treated warts were completely cleared within 60 days. NPS therapy can be used to treat cellular lesions in the epidermis and dermis without affecting noncellular components such as collagen and fibrin.
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spelling pubmed-83702932021-08-31 Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions Nuccitelli, Richard Bioelectricity Reviews Nano-Pulse Stimulation (NPS) therapy applies nanosecond pulsed electric fields to cells and tissues. It is a nonthermal modality that uses ultrashort pulses of electrical energy in the nanosecond domain. The cellular response to this therapy can be quite varied depending on the number of pulses applied and the total energy delivered. Reviewed in this study are some clinical trial data describing the effects of NPS therapy on normal skin as well as three different skin lesions as part of the first commercial application of this technology. NPS therapy has been found to clear seborrheic keratosis lesions with an 82% efficacy and sebaceous gland hyperplasia with a 99.5% efficacy. Pilot studies on warts indicated that 60% of the NPS-treated warts were completely cleared within 60 days. NPS therapy can be used to treat cellular lesions in the epidermis and dermis without affecting noncellular components such as collagen and fibrin. Mary Ann Liebert, Inc., publishers 2019-12-01 2019-12-12 /pmc/articles/PMC8370293/ /pubmed/34471826 http://dx.doi.org/10.1089/bioe.2019.0027 Text en © Richard Nuccitelli 2019; Published by Mary Ann Liebert, Inc. https://creativecommons.org/licenses/by/4.0/This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Nuccitelli, Richard
Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions
title Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions
title_full Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions
title_fullStr Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions
title_full_unstemmed Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions
title_short Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions
title_sort nano-pulse stimulation therapy for the treatment of skin lesions
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370293/
https://www.ncbi.nlm.nih.gov/pubmed/34471826
http://dx.doi.org/10.1089/bioe.2019.0027
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