Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions
Nano-Pulse Stimulation (NPS) therapy applies nanosecond pulsed electric fields to cells and tissues. It is a nonthermal modality that uses ultrashort pulses of electrical energy in the nanosecond domain. The cellular response to this therapy can be quite varied depending on the number of pulses appl...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Mary Ann Liebert, Inc., publishers
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370293/ https://www.ncbi.nlm.nih.gov/pubmed/34471826 http://dx.doi.org/10.1089/bioe.2019.0027 |
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author | Nuccitelli, Richard |
author_facet | Nuccitelli, Richard |
author_sort | Nuccitelli, Richard |
collection | PubMed |
description | Nano-Pulse Stimulation (NPS) therapy applies nanosecond pulsed electric fields to cells and tissues. It is a nonthermal modality that uses ultrashort pulses of electrical energy in the nanosecond domain. The cellular response to this therapy can be quite varied depending on the number of pulses applied and the total energy delivered. Reviewed in this study are some clinical trial data describing the effects of NPS therapy on normal skin as well as three different skin lesions as part of the first commercial application of this technology. NPS therapy has been found to clear seborrheic keratosis lesions with an 82% efficacy and sebaceous gland hyperplasia with a 99.5% efficacy. Pilot studies on warts indicated that 60% of the NPS-treated warts were completely cleared within 60 days. NPS therapy can be used to treat cellular lesions in the epidermis and dermis without affecting noncellular components such as collagen and fibrin. |
format | Online Article Text |
id | pubmed-8370293 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Mary Ann Liebert, Inc., publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-83702932021-08-31 Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions Nuccitelli, Richard Bioelectricity Reviews Nano-Pulse Stimulation (NPS) therapy applies nanosecond pulsed electric fields to cells and tissues. It is a nonthermal modality that uses ultrashort pulses of electrical energy in the nanosecond domain. The cellular response to this therapy can be quite varied depending on the number of pulses applied and the total energy delivered. Reviewed in this study are some clinical trial data describing the effects of NPS therapy on normal skin as well as three different skin lesions as part of the first commercial application of this technology. NPS therapy has been found to clear seborrheic keratosis lesions with an 82% efficacy and sebaceous gland hyperplasia with a 99.5% efficacy. Pilot studies on warts indicated that 60% of the NPS-treated warts were completely cleared within 60 days. NPS therapy can be used to treat cellular lesions in the epidermis and dermis without affecting noncellular components such as collagen and fibrin. Mary Ann Liebert, Inc., publishers 2019-12-01 2019-12-12 /pmc/articles/PMC8370293/ /pubmed/34471826 http://dx.doi.org/10.1089/bioe.2019.0027 Text en © Richard Nuccitelli 2019; Published by Mary Ann Liebert, Inc. https://creativecommons.org/licenses/by/4.0/This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Nuccitelli, Richard Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions |
title | Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions |
title_full | Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions |
title_fullStr | Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions |
title_full_unstemmed | Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions |
title_short | Nano-Pulse Stimulation Therapy for the Treatment of Skin Lesions |
title_sort | nano-pulse stimulation therapy for the treatment of skin lesions |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370293/ https://www.ncbi.nlm.nih.gov/pubmed/34471826 http://dx.doi.org/10.1089/bioe.2019.0027 |
work_keys_str_mv | AT nuccitellirichard nanopulsestimulationtherapyforthetreatmentofskinlesions |