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Psychological stress and cancer: new evidence of an increasingly strong link

To date stress, a highly complex process that disrupts homeostasis and involves environmental and psychosocial factors, is considered as one of the most crucial factor that affects our daily life, especially urban dweller’s life. Clinical and experimental studies widely support the notion that adren...

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Detalles Bibliográficos
Autores principales: Abate, M, Citro, M, Caputo, M, Pisanti, S, Martinelli, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università di Salerno 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370516/
https://www.ncbi.nlm.nih.gov/pubmed/33457324
http://dx.doi.org/10.37825/2239-9747.1010
Descripción
Sumario:To date stress, a highly complex process that disrupts homeostasis and involves environmental and psychosocial factors, is considered as one of the most crucial factor that affects our daily life, especially urban dweller’s life. Clinical and experimental studies widely support the notion that adrenergic stimulation due to chronic stress affects inflammation and metabolism. In this work, supported by several recent scientific evidences, we show how stress plays a positive role in cancer initiation, progression and cancer metastasis, a negative role for anti-tumor immune function and therapy response. Understanding the intricacies of this interaction could provide an additional help on how act in cancer prevention and therapy.