Cargando…

Antibodies against type I interferon: detection and association with severe clinical outcome in COVID‐19 patients

OBJECTIVES: Impairment of type I interferon (IFN‐I) immunity has been reported in critically ill COVID‐19 patients. This defect can be explained in a subset of patients by the presence of circulating autoantibodies (auto‐Abs) against IFN‐I. We set out to improve the detection and the quantification...

Descripción completa

Detalles Bibliográficos
Autores principales: Goncalves, David, Mezidi, Mehdi, Bastard, Paul, Perret, Magali, Saker, Kahina, Fabien, Nicole, Pescarmona, Rémi, Lombard, Christine, Walzer, Thierry, Casanova, Jean‐Laurent, Belot, Alexandre, Richard, Jean‐Christophe, Trouillet‐Assant, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370568/
https://www.ncbi.nlm.nih.gov/pubmed/34429968
http://dx.doi.org/10.1002/cti2.1327