Increased Expression of IL-10 in Peripheral Blood Mononuclear Cells Correlates with Negative Interferon-γ Release Assay Results in Culture-Confirmed Tuberculosis Patients

INTRODUCTION: Interferon-γ release assays (IGRAs) can have high false-negative rates for active tuberculosis (TB) cases. Here we investigated factors, including potential anti-inflammatory mechanisms, that contributed to false-negative IGRA results. METHODS: We established two cohorts. In the first...

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Detalles Bibliográficos
Autores principales: Guo, Jidong, Li, Qiang, Zhang, Xuxia, Yao, Cong, Liu, Rongmei, Pang, Yu, Gao, Mengqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370592/
https://www.ncbi.nlm.nih.gov/pubmed/34413657
http://dx.doi.org/10.2147/IDR.S314084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370592/
https://www.ncbi.nlm.nih.gov/pubmed/34413657
http://dx.doi.org/10.2147/IDR.S314084

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