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Developmental malformations resulting from high-dose maternal tamoxifen exposure in the mouse

Tamoxifen is an estrogen receptor (ER) ligand with widespread use in clinical and basic research settings. Beyond its application in treating ER-positive cancer, tamoxifen has been co-opted into a powerful approach for temporal-specific genetic alteration. The use of tamoxifen-inducible Cre-recombin...

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Detalles Bibliográficos
Autores principales: Sun, Miranda R., Steward, Austin C., Sweet, Emma A., Martin, Alexander A., Lipinski, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370643/
https://www.ncbi.nlm.nih.gov/pubmed/34403436
http://dx.doi.org/10.1371/journal.pone.0256299