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Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing
TNRC6 is a scaffolding protein that bridges interactions between small RNAs, argonaute (AGO) protein, and effector proteins to control gene expression. There are three paralogs in mammalian cells, TNRC6A, TNRC6B, and TNRC6C. These paralogs have ∼40% amino acid sequence identity and the extent of the...
Autores principales: | Johnson, Samantha T., Chu, Yongjun, Liu, Jing, Corey, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370741/ https://www.ncbi.nlm.nih.gov/pubmed/34108231 http://dx.doi.org/10.1261/rna.078709.121 |
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