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The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes

Connections between distinct catalytic RNA motifs through networks of mutations that retain catalytic function (neutral networks) were likely central to the evolution of biocatalysis. Despite suggestions that functional RNAs collectively form an interconnected web of neutral networks, little evidenc...

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Detalles Bibliográficos
Autores principales: DasGupta, Saurja, Nykiel, Kamila, Piccirilli, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370743/
https://www.ncbi.nlm.nih.gov/pubmed/34131025
http://dx.doi.org/10.1261/rna.078813.121

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