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The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes
Connections between distinct catalytic RNA motifs through networks of mutations that retain catalytic function (neutral networks) were likely central to the evolution of biocatalysis. Despite suggestions that functional RNAs collectively form an interconnected web of neutral networks, little evidenc...
Autores principales: | DasGupta, Saurja, Nykiel, Kamila, Piccirilli, Joseph A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370743/ https://www.ncbi.nlm.nih.gov/pubmed/34131025 http://dx.doi.org/10.1261/rna.078813.121 |
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