Long-circulating XTEN864-annexin A5 fusion protein for phosphatidylserine-related therapeutic applications

Annexin A5 (anxA5) is a marker for apoptosis, but has also therapeutic potential in cardiovascular diseases, cancer, and, due to apoptotic mimicry, against dangerous viruses, which is limited by the short blood circulation. An 864-amino-acid XTEN polypeptide was fused to anxA5. XTEN864-anxA5 was exp...

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Detalles Bibliográficos
Autores principales: Haeckel, Akvile, Ascher, Lena, Beindorff, Nicola, Prasad, Sonal, Garczyńska, Karolina, Guo, Jing, Schellenberger, Eyk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370750/
https://www.ncbi.nlm.nih.gov/pubmed/34405304
http://dx.doi.org/10.1007/s10495-021-01686-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370750/
https://www.ncbi.nlm.nih.gov/pubmed/34405304
http://dx.doi.org/10.1007/s10495-021-01686-w

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