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Long-circulating XTEN864-annexin A5 fusion protein for phosphatidylserine-related therapeutic applications

Annexin A5 (anxA5) is a marker for apoptosis, but has also therapeutic potential in cardiovascular diseases, cancer, and, due to apoptotic mimicry, against dangerous viruses, which is limited by the short blood circulation. An 864-amino-acid XTEN polypeptide was fused to anxA5. XTEN864-anxA5 was exp...

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Detalles Bibliográficos
Autores principales:	Haeckel, Akvile, Ascher, Lena, Beindorff, Nicola, Prasad, Sonal, Garczyńska, Karolina, Guo, Jing, Schellenberger, Eyk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370750/ https://www.ncbi.nlm.nih.gov/pubmed/34405304 http://dx.doi.org/10.1007/s10495-021-01686-w

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