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McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation
In Gram-positive bacteria, the McsB protein arginine kinase is central to protein quality control, labeling aberrant molecules for degradation by the ClpCP protease. Despite its importance for stress response and pathogenicity, it is still elusive how the bacterial degradation labeling is regulated....
Autores principales: | Hajdusits, Bence, Suskiewicz, Marcin J, Hundt, Nikolas, Meinhart, Anton, Kurzbauer, Robert, Leodolter, Julia, Kukura, Philipp, Clausen, Tim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370763/ https://www.ncbi.nlm.nih.gov/pubmed/34328418 http://dx.doi.org/10.7554/eLife.63505 |
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