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Receptor repertoires of murine follicular T helper cells reveal a high clonal overlap in separate lymph nodes in autoimmunity

Follicular T helper cells (Tfh) are a specialized subset of CD4 effector T cells that are crucial for germinal center (GC) reactions and for selecting B cells to undergo affinity maturation. Despite this central role for humoral immunity, only few data exist about their clonal distribution when mult...

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Detalles Bibliográficos
Autores principales: Niebuhr, Markus, Belde, Julia, Fähnrich, Anke, Serge, Arnauld, Irla, Magali, Ellebrecht, Christoph T, Hammers, Christoph M, Bieber, Katja, Westermann, Jürgen, Kalies, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370764/
https://www.ncbi.nlm.nih.gov/pubmed/34402793
http://dx.doi.org/10.7554/eLife.70053