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Smart Polymeric Nanoparticles with pH-Responsive and PEG-Detachable Properties (II): Co-Delivery of Paclitaxel and VEGF siRNA for Synergistic Breast Cancer Therapy in Mice

BACKGROUND: The dual-loaded nano-delivery system can realize chemotherapeutic drug and small interfering RNA (siRNA) co-loading as well as enhance the therapeutic effect of drugs on tumors through a synergistic effect, while reducing their toxic and side effects on normal tissues. METHODS: Previousl...

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Detalles Bibliográficos
Autores principales: Jin, Mingji, Hou, Yan, Quan, Xiuquan, Chen, Liqing, Gao, Zhonggao, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370882/
https://www.ncbi.nlm.nih.gov/pubmed/34413645
http://dx.doi.org/10.2147/IJN.S313339

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