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The role of cGMP-signalling and calcium-signalling in photoreceptor cell death: perspectives for therapy development
The second messengers, cGMP and Ca(2+), have both been implicated in retinal degeneration; however, it is still unclear which of the two is most relevant for photoreceptor cell death. This problem is exacerbated by the close connections and crosstalk between cGMP-signalling and calcium (Ca(2+))-sign...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370896/ https://www.ncbi.nlm.nih.gov/pubmed/33864120 http://dx.doi.org/10.1007/s00424-021-02556-9 |