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The role of cGMP-signalling and calcium-signalling in photoreceptor cell death: perspectives for therapy development

The second messengers, cGMP and Ca(2+), have both been implicated in retinal degeneration; however, it is still unclear which of the two is most relevant for photoreceptor cell death. This problem is exacerbated by the close connections and crosstalk between cGMP-signalling and calcium (Ca(2+))-sign...

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Detalles Bibliográficos
Autores principales: Das, Soumyaparna, Chen, Yiyi, Yan, Jie, Christensen, Gustav, Belhadj, Soumaya, Tolone, Arianna, Paquet-Durand, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370896/
https://www.ncbi.nlm.nih.gov/pubmed/33864120
http://dx.doi.org/10.1007/s00424-021-02556-9

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