Lysosome purinergic receptor P2X4 regulates neoangiogenesis induced by microvesicles from sarcoma patients

The tumor microenvironment modulates cancer growth. Extracellular vesicles (EVs) have been identified as key mediators of intercellular communication, but their role in tumor growth is largely unexplored. Here, we demonstrate that EVs from sarcoma patients promote neoangiogenesis via a purinergic X...

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Detalles Bibliográficos
Autores principales: Palinski, Wulf, Monti, Maria, Camerlingo, Rosa, Iacobucci, Ilaria, Bocella, Serena, Pinto, Federica, Iannuzzi, Clara, Mansueto, Gelsomina, Pignatiello, Sara, Fazioli, Flavio, Gallo, Michele, Marra, Laura, Cozzolino, Flora, De Chiara, Annarosaria, Pucci, Piero, Bilancio, Antonio, de Nigris, Filomena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371002/
https://www.ncbi.nlm.nih.gov/pubmed/34404763
http://dx.doi.org/10.1038/s41419-021-04069-w

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