Cargando…

A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants

The successive emergences and accelerating spread of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages and evolved resistance to some ongoing clinical therapeutics increase the risks associated with the coronavirus disease 2019 (COVID-19) pandemic. An urgent intervention fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Yanyun, Shi, Rui, Zhang, Ying, Duan, Xiaomin, Li, Li, Zhang, Jing, Wang, Fengze, Zhang, Ruixue, Shen, Hao, Wang, Yue, Wu, Zheng, Peng, Qianwen, Pan, Ting, Sun, Wanwei, Huang, Weijin, Feng, Yue, Feng, Hui, Xiao, Junyu, Tan, Wenjie, Wang, Youchun, Wang, Chenhui, Yan, Jinghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371079/ https://www.ncbi.nlm.nih.gov/pubmed/34404805 http://dx.doi.org/10.1038/s41467-021-25331-x

Ejemplares similares

A non-ACE2-blocking neutralizing antibody against Omicron-included SARS-CoV-2 variants
por: Duan, Xiaomin, et al.
Publicado: (2022)

ACE2 decoy receptor generated by high-throughput saturation mutagenesis efficiently neutralizes SARS-CoV-2 and its prevalent variants
por: Wang, Bolun, et al.
Publicado: (2022)

Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies
por: Wang, Yifan, et al.
Publicado: (2022)

Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants
por: Wang, Fengze, et al.
Publicado: (2022)

Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants
por: Du, Shuo, et al.
Publicado: (2021)

Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry
por: Park, Young-Jun, et al.
Publicado: (2021)

Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry
por: Park, Young-Jun, et al.
Publicado: (2022)

ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker
por: Chen, Yuning, et al.
Publicado: (2021)

A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD
por: Liu, Shuo, et al.
Publicado: (2022)

An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants
por: Liu, Juan, et al.
Publicado: (2023)

Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization
por: Zhang, Li, et al.
Publicado: (2021)

Development of a Triple-Color Pseudovirion-Based Assay to Detect Neutralizing Antibodies against Human Papillomavirus
por: Nie, Jianhui, et al.
Publicado: (2016)

Distinct BCR repertoires elicited by SARS-CoV-2 RBD and S vaccinations in mice
por: Tian, Siyu, et al.
Publicado: (2021)

A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2
por: Huang, Qingrui, et al.
Publicado: (2021)

Antibody Cocktail Exhibits Broad Neutralization Activity Against SARS-CoV-2 and SARS-CoV-2 Variants
por: Qu, Yuanyuan, et al.
Publicado: (2021)

Publisher Correction: A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2
por: Huang, Qingrui, et al.
Publicado: (2021)

Reduced sensitivity of the SARS-CoV-2 Lambda variant to monoclonal antibodies and neutralizing antibodies induced by infection and vaccination
por: Wang, Meiyu, et al.
Publicado: (2021)

ACE2 binding and antibody evasion in enhanced transmissibility of XBB.1.5
por: Yue, Can, et al.
Publicado: (2023)

Lentil lectin derived from Lens culinaris exhibit broad antiviral activities against SARS-CoV-2 variants
por: Wang, Wenbo, et al.
Publicado: (2021)

Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents
por: Cao, Yunlong, et al.
Publicado: (2022)

ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies
por: Low, Jun Siong, et al.
Publicado: (2022)

Sera from breakthrough infections with SARS-CoV-2 BA.5 or BF.7 showed lower neutralization activity against XBB.1.5 and CH.1.1
por: Liu, Shuo, et al.
Publicado: (2023)

Broad host tropism of ACE2-using MERS-related coronaviruses and determinants restricting viral recognition
por: Ma, Chengbao, et al.
Publicado: (2023)

Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2
por: Wu, Lili, et al.
Publicado: (2020)

The first Chinese national standards for SARS-CoV-2 neutralizing antibody
por: Guan, Lidong, et al.
Publicado: (2021)

Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry
por: Ge, Jiwan, et al.
Publicado: (2021)

Structural characterization of a neutralizing mAb H16.001, a potent candidate for a common potency assay for various HPV16 VLPs
por: Huang, Weijin, et al.
Publicado: (2020)

Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2
por: Nie, Jianhui, et al.
Publicado: (2020)

DOCK2 regulates antifungal immunity by regulating RAC GTPase activity
por: Ma, Xiaojian, et al.
Publicado: (2022)

An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern
por: Du, Wenjuan, et al.
Publicado: (2022)

Clofazimine derivatives as potent broad-spectrum antiviral agents with dual-target mechanism
por: Zhang, Xintong, et al.
Publicado: (2022)

A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants
por: Yang, Zhenlin, et al.
Publicado: (2021)

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
por: Cao, Yunlong, et al.
Publicado: (2021)

Broadly Effective ACE2 Decoy Proteins Protect Mice from Lethal SARS-CoV-2 Infection
por: Lu, Mengjia, et al.
Publicado: (2023)

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
por: Wu, Yan, et al.
Publicado: (2020)

A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency
por: Leach, Adam, et al.
Publicado: (2021)

Multimeric ACE2-IgM fusions as broadly active antivirals that potently neutralize SARS-CoV-2 variants
por: Svilenov, Hristo L., et al.
Publicado: (2022)

Identification of Broad-Genotype HPV L2 Neutralization Site for Pan-HPV Vaccine Development by a Cross-Neutralizing Antibody
por: Wang, Daning, et al.
Publicado: (2015)

Analysis of SARS-CoV-2 variants B.1.617: host tropism, proteolytic activation, cell–cell fusion, and neutralization sensitivity
por: Zhang, Li, et al.
Publicado: (2022)

Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2
por: Liu, Yinghui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_46mf9o6gag42nedmfu272ag042