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Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids

To construct a superior microbial cell factory for chemical synthesis, a major challenge is to fully exploit cellular potential by identifying and engineering beneficial gene targets in sophisticated metabolic networks. Here, we take advantage of CRISPR interference (CRISPRi) and omics analyses to s...

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Detalles Bibliográficos
Autores principales: Fang, Lixia, Fan, Jie, Luo, Shulei, Chen, Yaru, Wang, Congya, Cao, Yingxiu, Song, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371096/
https://www.ncbi.nlm.nih.gov/pubmed/34404790
http://dx.doi.org/10.1038/s41467-021-25243-w

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