Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes

A cell’s phenotype and function are influenced by dynamic interactions with its microenvironment. To examine cellular spatiotemporal activity, we developed SPACECAT—Spatially PhotoActivatable Color Encoded Cell Address Tags—to annotate, track, and isolate cells while preserving viability. In SPACECA...

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Detalles Bibliográficos
Autores principales: Genshaft, Alex S, Ziegler, Carly G. K., Tzouanas, Constantine N., Mead, Benjamin E., Jaeger, Alex M., Navia, Andrew W., King, Ryan P., Mana, Miyeko D., Huang, Siyi, Mitsialis, Vanessa, Snapper, Scott B., Yilmaz, Ömer H., Jacks, Tyler, Van Humbeck, Jeffrey F., Shalek, Alex K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371137/
https://www.ncbi.nlm.nih.gov/pubmed/34404785
http://dx.doi.org/10.1038/s41467-021-25279-y

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