Differential mitochondrial roles for α-synuclein in DRP1-dependent fission and PINK1/Parkin-mediated oxidation

Mitochondria are highly dynamic organelles with strict quality control processes that maintain cellular homeostasis. Within axons, coordinated cycles of fission-fusion mediated by dynamin related GTPase protein (DRP1) and mitofusins (MFN), together with regulated motility of healthy mitochondria ant...

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Detalles Bibliográficos
Autores principales: Krzystek, Thomas J., Banerjee, Rupkatha, Thurston, Layne, Huang, JianQiao, Swinter, Kelsey, Rahman, Saad Navid, Falzone, Tomas L., Gunawardena, Shermali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371151/
https://www.ncbi.nlm.nih.gov/pubmed/34404758
http://dx.doi.org/10.1038/s41419-021-04046-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371151/
https://www.ncbi.nlm.nih.gov/pubmed/34404758
http://dx.doi.org/10.1038/s41419-021-04046-3

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