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Transcriptomic analysis of the mouse retina after acute and chronic normobaric and hypobaric hypoxia
Oxygen delivery to the retinal pigment epithelium and the outer retina is essential for metabolism, function, and survival of photoreceptors. Chronically reduced oxygen supply leads to retinal pathologies in patients and causes age-dependent retinal degeneration in mice. Hypoxia can result from decr...
Autores principales: | Ebner, L. J. A., Samardzija, M., Storti, F., Todorova, V., Karademir, D., Behr, J., Simpson, F., Thiersch, M., Grimm, C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371159/ https://www.ncbi.nlm.nih.gov/pubmed/34404875 http://dx.doi.org/10.1038/s41598-021-96150-9 |
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