Cargando…

Effect of erythropoietin administration on the expression of brain-derived neurotrophic factor, stromal cell-derived Factor-1, and neuron-specific enolase in traumatic brain injury: A literature review

Traumatic brain injury (TBI) is a major cause of death and lifelong disability around the world that predominantly affects young and middle-aged people. Erythropoietin (EPO) is a promising therapeutic agent for a variety of neurological injuries including TBI due to its neuroprotective effects. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Said, Muhammad Fadli, Islam, Andi Asadul, Massi, Muhammad Nasrum, Prihantono
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371185/
https://www.ncbi.nlm.nih.gov/pubmed/34429948
http://dx.doi.org/10.1016/j.amsu.2021.102666
_version_ 1783739587983572992
author Said, Muhammad Fadli
Islam, Andi Asadul
Massi, Muhammad Nasrum
Prihantono
author_facet Said, Muhammad Fadli
Islam, Andi Asadul
Massi, Muhammad Nasrum
Prihantono
author_sort Said, Muhammad Fadli
collection PubMed
description Traumatic brain injury (TBI) is a major cause of death and lifelong disability around the world that predominantly affects young and middle-aged people. Erythropoietin (EPO) is a promising therapeutic agent for a variety of neurological injuries including TBI due to its neuroprotective effects. Here we review the impact of exogenous erythropoietin administration on the expression of brain-derived neurotrophic factor (BDNF), stromal cell-derived factor-1 (SDF-1), and neuron-specific enolase (NSE) levels in cerebrospinal fluid after TBI as biomarkers for neuron regeneration and survival to predict TBI outcome.
format Online
Article
Text
id pubmed-8371185
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-83711852021-08-23 Effect of erythropoietin administration on the expression of brain-derived neurotrophic factor, stromal cell-derived Factor-1, and neuron-specific enolase in traumatic brain injury: A literature review Said, Muhammad Fadli Islam, Andi Asadul Massi, Muhammad Nasrum Prihantono Ann Med Surg (Lond) Review Traumatic brain injury (TBI) is a major cause of death and lifelong disability around the world that predominantly affects young and middle-aged people. Erythropoietin (EPO) is a promising therapeutic agent for a variety of neurological injuries including TBI due to its neuroprotective effects. Here we review the impact of exogenous erythropoietin administration on the expression of brain-derived neurotrophic factor (BDNF), stromal cell-derived factor-1 (SDF-1), and neuron-specific enolase (NSE) levels in cerebrospinal fluid after TBI as biomarkers for neuron regeneration and survival to predict TBI outcome. Elsevier 2021-08-05 /pmc/articles/PMC8371185/ /pubmed/34429948 http://dx.doi.org/10.1016/j.amsu.2021.102666 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Said, Muhammad Fadli
Islam, Andi Asadul
Massi, Muhammad Nasrum
Prihantono
Effect of erythropoietin administration on the expression of brain-derived neurotrophic factor, stromal cell-derived Factor-1, and neuron-specific enolase in traumatic brain injury: A literature review
title Effect of erythropoietin administration on the expression of brain-derived neurotrophic factor, stromal cell-derived Factor-1, and neuron-specific enolase in traumatic brain injury: A literature review
title_full Effect of erythropoietin administration on the expression of brain-derived neurotrophic factor, stromal cell-derived Factor-1, and neuron-specific enolase in traumatic brain injury: A literature review
title_fullStr Effect of erythropoietin administration on the expression of brain-derived neurotrophic factor, stromal cell-derived Factor-1, and neuron-specific enolase in traumatic brain injury: A literature review
title_full_unstemmed Effect of erythropoietin administration on the expression of brain-derived neurotrophic factor, stromal cell-derived Factor-1, and neuron-specific enolase in traumatic brain injury: A literature review
title_short Effect of erythropoietin administration on the expression of brain-derived neurotrophic factor, stromal cell-derived Factor-1, and neuron-specific enolase in traumatic brain injury: A literature review
title_sort effect of erythropoietin administration on the expression of brain-derived neurotrophic factor, stromal cell-derived factor-1, and neuron-specific enolase in traumatic brain injury: a literature review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371185/
https://www.ncbi.nlm.nih.gov/pubmed/34429948
http://dx.doi.org/10.1016/j.amsu.2021.102666
work_keys_str_mv AT saidmuhammadfadli effectoferythropoietinadministrationontheexpressionofbrainderivedneurotrophicfactorstromalcellderivedfactor1andneuronspecificenolaseintraumaticbraininjuryaliteraturereview
AT islamandiasadul effectoferythropoietinadministrationontheexpressionofbrainderivedneurotrophicfactorstromalcellderivedfactor1andneuronspecificenolaseintraumaticbraininjuryaliteraturereview
AT massimuhammadnasrum effectoferythropoietinadministrationontheexpressionofbrainderivedneurotrophicfactorstromalcellderivedfactor1andneuronspecificenolaseintraumaticbraininjuryaliteraturereview
AT prihantono effectoferythropoietinadministrationontheexpressionofbrainderivedneurotrophicfactorstromalcellderivedfactor1andneuronspecificenolaseintraumaticbraininjuryaliteraturereview