Mycobacterium tuberculosis SufR responds to nitric oxide via its 4Fe–4S cluster and regulates Fe–S cluster biogenesis for persistence in mice

The persistence of Mycobacterium tuberculosis (Mtb) is a major problem in managing tuberculosis (TB). Host-generated nitric oxide (NO) is perceived as one of the signals by Mtb to reprogram metabolism and respiration for persistence. However, the mechanisms involved in NO sensing and reorganizing Mt...

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Detalles Bibliográficos
Autores principales: Anand, Kushi, Tripathi, Ashutosh, Shukla, Kaustubh, Malhotra, Nitish, Jamithireddy, Anil Kumar, Jha, Rajiv Kumar, Chaudhury, Susmit Narayan, Rajmani, Raju S., Ramesh, Arati, Nagaraja, Valakunja, Gopal, Balasubramanian, Nagaraju, Ganesh, Narain Seshayee, Aswin Sai, Singh, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371249/
https://www.ncbi.nlm.nih.gov/pubmed/34392160
http://dx.doi.org/10.1016/j.redox.2021.102062

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