Replication/Assembly Defective Avian Flavivirus With Internal Deletions in the Capsid Can Be Used as an Approach for Living Attenuated Vaccine

Avian Tembusu virus (TMUV) is a novel flavivirus causing severe egg drop and fatal encephalitis in avian in Asia. In the present study, we screened the structural and functional requirements of TMUV capsid protein (CP) for viral morphogenesis using reverse genetics methods in combination with replic...

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Detalles Bibliográficos
Autores principales: He, Yu, Wang, Xiaoli, Guo, Jiaqi, Mao, Li, Zhang, Senzhao, Hu, Tao, Wang, Mingshu, Jia, Renyong, Zhu, Dekang, Liu, Mafeng, Zhao, Xinxin, Yang, Qiao, Wu, Ying, Zhang, Shaqiu, Huang, Juan, Mao, Sai, Ou, Xumin, Gao, Qun, Sun, Di, Liu, Yunya, Zhang, Ling, Yu, Yanling, Cheng, Anchun, Chen, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371329/
https://www.ncbi.nlm.nih.gov/pubmed/34421904
http://dx.doi.org/10.3389/fimmu.2021.694959

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