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Muscle‐specific sirtuin 3 overexpression does not attenuate the pathological effects of high‐fat/high‐sucrose feeding but does enhance cardiac SERCA2a activity

Obesity, type 2 diabetes, and heart disease are linked to an unhealthy diet. Sarco(endo)plasmic reticulum calcium (Ca(2+)) ATPase 2a (SERCA2a) controls cardiac function by transporting Ca(2+) in cardiomyocytes. SERCA2a is altered by diet and acetylation, independently; however, it is unknown if diet...

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Detalles Bibliográficos
Autores principales:	Oldfield, Christopher J., Moffatt, Teri L., O'Hara, Kimberley A., Xiang, Bo, Dolinsky, Vernon W., Duhamel, Todd A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371348/ https://www.ncbi.nlm.nih.gov/pubmed/34405591 http://dx.doi.org/10.14814/phy2.14961

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