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The myosin activator omecamtiv mecarbil improves wall stress in a rat model of chronic aortic regurgitation

In patients with chronic aortic regurgitation (AR), excessive preload and afterload increase left ventricle wall stress, leading to left ventricular systolic dysfunction. Thus, the objective of the present study was to evaluate the effects of the myosin activator omecamtiv mecarbil (OM) on left vent...

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Detalles Bibliográficos
Autores principales: El Oumeiri, Bachar, van de Borne, Philippe, Hubesch, Géraldine, Herpain, Antoine, Annoni, Filippo, Jespers, Pascale, Stefanidis, Constantin, Mc Entee, Kathleen, Vanden Eynden, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371349/
https://www.ncbi.nlm.nih.gov/pubmed/34405966
http://dx.doi.org/10.14814/phy2.14988