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The myosin activator omecamtiv mecarbil improves wall stress in a rat model of chronic aortic regurgitation
In patients with chronic aortic regurgitation (AR), excessive preload and afterload increase left ventricle wall stress, leading to left ventricular systolic dysfunction. Thus, the objective of the present study was to evaluate the effects of the myosin activator omecamtiv mecarbil (OM) on left vent...
Autores principales: | El Oumeiri, Bachar, van de Borne, Philippe, Hubesch, Géraldine, Herpain, Antoine, Annoni, Filippo, Jespers, Pascale, Stefanidis, Constantin, Mc Entee, Kathleen, Vanden Eynden, Frédéric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371349/ https://www.ncbi.nlm.nih.gov/pubmed/34405966 http://dx.doi.org/10.14814/phy2.14988 |
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