Uncharged Components of Single-Stranded DNA Modulate Liquid–Liquid Phase Separation With Cationic Linker Histone H1

Liquid–liquid phase separation (LLPS) of proteins and DNAs has been recognized as a fundamental mechanism for the formation of intracellular biomolecular condensates. Here, we show the role of the constituent DNA components, i.e., the phosphate groups, deoxyribose sugars, and nucleobases, in LLPS wi...

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Detalles Bibliográficos
Autores principales: Mimura, Masahiro, Tomita, Shunsuke, Sugai, Hiroka, Shinkai, Yoichi, Ishihara, Sayaka, Kurita, Ryoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371396/
https://www.ncbi.nlm.nih.gov/pubmed/34422830
http://dx.doi.org/10.3389/fcell.2021.710729

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