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Early high-dose vitamin C in post-cardiac arrest syndrome (VITaCCA): study protocol for a randomized, double-blind, multi-center, placebo-controlled trial
BACKGROUND: High-dose intravenous vitamin C directly scavenges and decreases the production of harmful reactive oxygen species (ROS) generated during ischemia/reperfusion after a cardiac arrest. The aim of this study is to investigate whether short-term treatment with a supplementary or very high-do...
Autores principales: | Rozemeijer, Sander, de Grooth, Harm-Jan, Elbers, Paul W. G., Girbes, Armand R. J., den Uil, Corstiaan A., Dubois, Eric A., Wils, Evert-Jan, Rettig, Thijs C. D., van Zanten, Arthur R. H., Vink, Roel, van den Bogaard, Bas, Bosman, Rob J., Oudemans-van Straaten, Heleen M., de Man, Angélique M. E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371424/ https://www.ncbi.nlm.nih.gov/pubmed/34407846 http://dx.doi.org/10.1186/s13063-021-05483-3 |
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