Hypericin Enhances Paclitaxel-Induced B16-F10 Cell Apoptosis by Activating a Cytochrome c Release–Dependent Pathway

The enhanced inhibitory effect of paclitaxel (PTX) combined with hypericin (HY) on B16-F10 cells may be realized through the ROS-related cytochrome c release pathway. The apoptotic characteristics of the B16-F10 cells, such as DNA fragmentation, chromatin condensation, and apoptotic body formation,...

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Detalles Bibliográficos
Autores principales: Sun, Liyun, Li, Zixuan, Shang, Huoli, Xin, Xiujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371448/
https://www.ncbi.nlm.nih.gov/pubmed/34421585
http://dx.doi.org/10.3389/fphar.2021.652452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371448/
https://www.ncbi.nlm.nih.gov/pubmed/34421585
http://dx.doi.org/10.3389/fphar.2021.652452

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