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Targeting Fatty Acid Synthase Modulates Metabolic Pathways and Inhibits Cholangiocarcinoma Cell Progression

An aberrant regulation of lipid metabolism is involved in the pathogenesis and progression of cancer. Up-regulation of lipid biosynthesis enzymes, including acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN) and HMG-CoA reductase (HMGCR), has been reported in many cancers. Therefore, elucidati...

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Detalles Bibliográficos
Autores principales:	Tomacha, Jittima, Dokduang, Hasaya, Padthaisong, Sureerat, Namwat, Nisana, Klanrit, Poramate, Phetcharaburanin, Jutarop, Wangwiwatsin, Arporn, Khampitak, Tueanjit, Koonmee, Supinda, Titapun, Attapol, Jarearnrat, Apiwat, Khuntikeo, Narong, Loilome, Watcharin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371458/ https://www.ncbi.nlm.nih.gov/pubmed/34421595 http://dx.doi.org/10.3389/fphar.2021.696961

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