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Screening for androgen agonists using autonomously bioluminescent HEK293 reporter cells
Due to the public health concerns of endocrine-disrupting chemicals, there is an increasing demand to develop improved high-throughput detection assays for enhanced exposure control and risk assessment. A substrate-free, autobioluminescent HEK293(ARE/Gal4-Lux) assay was developed to screen compounds...
Autores principales: | Xu, Tingting, Gilliam, Madison, Sayler, Gary, Ripp, Steven, Close, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371548/ https://www.ncbi.nlm.nih.gov/pubmed/34350768 http://dx.doi.org/10.2144/btn-2021-0017 |
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