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Alanine Represses γ-Aminobutyric Acid Utilization and Induces Alanine Transaminase Required for Mitochondrial Function in Saccharomyces cerevisiae

The γ-aminobutyric acid (GABA) shunt constitutes a conserved metabolic route generating nicotinamide adenine dinucleotide phosphate (NADPH) and regulating stress response in most organisms. Here we show that in the presence of GABA, Saccharomyces cerevisiae produces glutamate and alanine through the...

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Detalles Bibliográficos
Autores principales: Márquez, Dariel, Escalera-Fanjul, Ximena, el Hafidi, Mohammed, Aguirre-López, Beatriz, Riego-Ruiz, Lina, González, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371705/
https://www.ncbi.nlm.nih.gov/pubmed/34421848
http://dx.doi.org/10.3389/fmicb.2021.695382