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Alanine Represses γ-Aminobutyric Acid Utilization and Induces Alanine Transaminase Required for Mitochondrial Function in Saccharomyces cerevisiae
The γ-aminobutyric acid (GABA) shunt constitutes a conserved metabolic route generating nicotinamide adenine dinucleotide phosphate (NADPH) and regulating stress response in most organisms. Here we show that in the presence of GABA, Saccharomyces cerevisiae produces glutamate and alanine through the...
Autores principales: | Márquez, Dariel, Escalera-Fanjul, Ximena, el Hafidi, Mohammed, Aguirre-López, Beatriz, Riego-Ruiz, Lina, González, Alicia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371705/ https://www.ncbi.nlm.nih.gov/pubmed/34421848 http://dx.doi.org/10.3389/fmicb.2021.695382 |
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