Insulin amyloid fibrils interact directly with the NLRP3, resulting in inflammasome activation and pyroptotic cell death

INTRODUCTION: Nucleotide-binding oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3), an intracellular pattern recognition receptor, recognizes various pathogen-associated molecular pattern and/or damage-associated molecular pattern molecules to constitute inflammasome tha...

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Detalles Bibliográficos
Autores principales: Mori, Wakako, Kaneko, Naoe, Nakanishi, Ayaka, Zako, Tamotsu, Masumoto, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371720/
https://www.ncbi.nlm.nih.gov/pubmed/34396831
http://dx.doi.org/10.1177/20587384211038357

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