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Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells

BACKGROUND: The mechanisms of endocrine resistance are complex, and deregulation of several oncogenic signalling pathways has been proposed. We aimed to investigate the role of the EGFR and Src-mediated STAT3 signalling pathway in tamoxifen-resistant breast cancer cells. METHODS: The ER-positive lum...

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Detalles Bibliográficos
Autores principales:	Moon, Seo Yun, Lee, Heejin, Kim, Seoree, Hong, Ji Hyung, Chun, Sang Hoon, Lee, Hee Yeon, Kang, Keunsoo, Kim, Ho Shik, Won, Hye Sung, Ko, Yoon Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371881/ https://www.ncbi.nlm.nih.gov/pubmed/34407787 http://dx.doi.org/10.1186/s12885-021-08641-7

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