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Bifurcation analysis of a discrete-time compartmental model for hypertensive or diabetic patients exposed to COVID-19
In this article, a mathematical model for hypertensive or diabetic patients open to COVID-19 is considered along with a set of first-order nonlinear differential equations. Moreover, the method of piecewise arguments is used to discretize the continuous system. The mathematical system is said to rev...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372232/ https://www.ncbi.nlm.nih.gov/pubmed/34426778 http://dx.doi.org/10.1140/epjp/s13360-021-01862-6 |
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author | Khan, Muhammad Salman samreen, Maria Ozair, Muhammad Hussain, Takasar Gómez-Aguilar, J. F. |
author_facet | Khan, Muhammad Salman samreen, Maria Ozair, Muhammad Hussain, Takasar Gómez-Aguilar, J. F. |
author_sort | Khan, Muhammad Salman |
collection | PubMed |
description | In this article, a mathematical model for hypertensive or diabetic patients open to COVID-19 is considered along with a set of first-order nonlinear differential equations. Moreover, the method of piecewise arguments is used to discretize the continuous system. The mathematical system is said to reveal six equilibria, namely, extinction equilibrium, boundary equilibrium, quarantined-free equilibrium, exposure-free equilibrium, endemic equilibrium, and the equilibrium free from susceptible population. Local stability conditions are developed for our discrete-time mathematical system about each of its equilibrium point. The existence of period-doubling bifurcation and chaos is studied in the absence of isolated population. It is shown that our system will become unstable and experiences the chaos when the quarantined compartment is empty, which is true in biological meanings. The existence of Neimark–Sacker bifurcation is studied for the endemic equilibrium point. Moreover, it is shown numerically that our discrete-time mathematical system experiences the period-doubling bifurcation about its endemic equilibrium. To control the period-doubling bifurcation, Neimark–Sacker bifurcation, a generalized hybrid control methodology is used. Moreover, this model is analyzed along with generalized hybrid control in order to eliminate chaos and oscillation epidemiologically presenting the significance of quarantine in the COVID-19 environment. |
format | Online Article Text |
id | pubmed-8372232 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-83722322021-08-19 Bifurcation analysis of a discrete-time compartmental model for hypertensive or diabetic patients exposed to COVID-19 Khan, Muhammad Salman samreen, Maria Ozair, Muhammad Hussain, Takasar Gómez-Aguilar, J. F. Eur Phys J Plus Regular Article In this article, a mathematical model for hypertensive or diabetic patients open to COVID-19 is considered along with a set of first-order nonlinear differential equations. Moreover, the method of piecewise arguments is used to discretize the continuous system. The mathematical system is said to reveal six equilibria, namely, extinction equilibrium, boundary equilibrium, quarantined-free equilibrium, exposure-free equilibrium, endemic equilibrium, and the equilibrium free from susceptible population. Local stability conditions are developed for our discrete-time mathematical system about each of its equilibrium point. The existence of period-doubling bifurcation and chaos is studied in the absence of isolated population. It is shown that our system will become unstable and experiences the chaos when the quarantined compartment is empty, which is true in biological meanings. The existence of Neimark–Sacker bifurcation is studied for the endemic equilibrium point. Moreover, it is shown numerically that our discrete-time mathematical system experiences the period-doubling bifurcation about its endemic equilibrium. To control the period-doubling bifurcation, Neimark–Sacker bifurcation, a generalized hybrid control methodology is used. Moreover, this model is analyzed along with generalized hybrid control in order to eliminate chaos and oscillation epidemiologically presenting the significance of quarantine in the COVID-19 environment. Springer Berlin Heidelberg 2021-08-18 2021 /pmc/articles/PMC8372232/ /pubmed/34426778 http://dx.doi.org/10.1140/epjp/s13360-021-01862-6 Text en © The Author(s), under exclusive licence to Società Italiana di Fisica and Springer-Verlag GmbH Germany, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Regular Article Khan, Muhammad Salman samreen, Maria Ozair, Muhammad Hussain, Takasar Gómez-Aguilar, J. F. Bifurcation analysis of a discrete-time compartmental model for hypertensive or diabetic patients exposed to COVID-19 |
title | Bifurcation analysis of a discrete-time compartmental model for hypertensive or diabetic patients exposed to COVID-19 |
title_full | Bifurcation analysis of a discrete-time compartmental model for hypertensive or diabetic patients exposed to COVID-19 |
title_fullStr | Bifurcation analysis of a discrete-time compartmental model for hypertensive or diabetic patients exposed to COVID-19 |
title_full_unstemmed | Bifurcation analysis of a discrete-time compartmental model for hypertensive or diabetic patients exposed to COVID-19 |
title_short | Bifurcation analysis of a discrete-time compartmental model for hypertensive or diabetic patients exposed to COVID-19 |
title_sort | bifurcation analysis of a discrete-time compartmental model for hypertensive or diabetic patients exposed to covid-19 |
topic | Regular Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372232/ https://www.ncbi.nlm.nih.gov/pubmed/34426778 http://dx.doi.org/10.1140/epjp/s13360-021-01862-6 |
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