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circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1

OBJECTIVES: Circular RNAs (circRNAs) have emerged as significant biological regulators. Herein, we aimed to elucidate the role of an unidentified circRNA (circPDE4B) that is reportedly downregulated in osteoarthritis (OA) tissues. METHODS: The effects of circPDE4B were explored in human and mouse ch...

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Detalles Bibliográficos
Autores principales:	Shen, Shuying, Yang, Yute, Shen, Panyang, Ma, Jun, Fang, Bin, Wang, Qingxin, Wang, Kefan, Shi, Peihua, Fan, Shunwu, Fang, Xiangqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Osteoarthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372377/ https://www.ncbi.nlm.nih.gov/pubmed/34039624 http://dx.doi.org/10.1136/annrheumdis-2021-219969

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