Dissecting the activation of insulin degrading enzyme by inositol pyrophosphates and their bisphosphonate analogs

Inositol poly- and pyrophosphates (InsPs and PP-InsPs) are densely phosphorylated eukaryotic messengers, which are involved in numerous cellular processes. To elucidate their signaling functions at the molecular level, non-hydrolyzable bisphosphonate analogs of inositol pyrophosphates, PCP-InsPs, ha...

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Detalles Bibliográficos
Autores principales: Hostachy, Sarah, Utesch, Tillmann, Franke, Katy, Dornan, Gillian Leigh, Furkert, David, Türkaydin, Berke, Haucke, Volker, Sun, Han, Fiedler, Dorothea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372538/
https://www.ncbi.nlm.nih.gov/pubmed/34476054
http://dx.doi.org/10.1039/d1sc02975d

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