Modeling Intrahippocampal Effects of Anterior Hippocampal Hyperactivity Relevant to Schizophrenia Using Chemogenetic Excitation of Long Axis–Projecting Mossy Cells in the Mouse Dentate Gyrus

BACKGROUND: The anterior hippocampus of individuals with early psychosis or schizophrenia is hyperactive, as is the ventral hippocampus in many rodent models for schizophrenia risk. Mossy cells (MCs) of the ventral dentate gyrus (DG) densely project in the hippocampal long axis, targeting both dorsa...

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Detalles Bibliográficos
Autores principales: Bauer, James P., Rader, Sarah L., Joffe, Max E., Kwon, Wooseok, Quay, Juliana, Seanez, Leann, Zhou, Chengwen, Conn, P. Jeffrey, Lewis, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Archival Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372626/
https://www.ncbi.nlm.nih.gov/pubmed/34414387
http://dx.doi.org/10.1016/j.bpsgos.2021.04.005

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