Experimental and mathematical evidence that thrombin-binding aptamers form a 1 aptamer:2 protein complex

The thrombin-binding 15mer and 29mer ssDNA aptamers are a widely used model system. Despite their ubiquity, controversies persist regarding the nature of the aptamer-protein interactions. Reported affinities vary widely; the role of metal ions in binding is unclear; the structure of the complex is c...

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Detalles Bibliográficos
Autores principales: Mears, Kepler S, Markus, Daniel L, Ogunjimi, Oluwadamilare, Whelan, Rebecca J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372783/
https://www.ncbi.nlm.nih.gov/pubmed/34414355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372783/
https://www.ncbi.nlm.nih.gov/pubmed/34414355

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