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Detoxification of methylglyoxal by the glyoxalase system is required for glutathione availability and virulence activation in Listeria monocytogenes

Listeria monocytogenes is a Gram-positive, food-borne pathogen that lives a biphasic lifestyle, cycling between the environment and as a facultative intracellular pathogen of mammals. Upon entry into host cells, L. monocytogenes upregulates expression of glutathione synthase (GshF) and its product,...

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Detalles Bibliográficos
Autores principales: Anaya-Sanchez, Andrea, Feng, Ying, Berude, John C., Portnoy, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372916/
https://www.ncbi.nlm.nih.gov/pubmed/34407151
http://dx.doi.org/10.1371/journal.ppat.1009819

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