Cargando…
Detoxification of methylglyoxal by the glyoxalase system is required for glutathione availability and virulence activation in Listeria monocytogenes
Listeria monocytogenes is a Gram-positive, food-borne pathogen that lives a biphasic lifestyle, cycling between the environment and as a facultative intracellular pathogen of mammals. Upon entry into host cells, L. monocytogenes upregulates expression of glutathione synthase (GshF) and its product,...
Autores principales: | Anaya-Sanchez, Andrea, Feng, Ying, Berude, John C., Portnoy, Daniel A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372916/ https://www.ncbi.nlm.nih.gov/pubmed/34407151 http://dx.doi.org/10.1371/journal.ppat.1009819 |
Ejemplares similares
-
Role of glyoxalase 1 in methylglyoxal detoxification–the broad player of psychiatric disorders
por: Toriumi, Kazuya, et al.
Publicado: (2021) -
PARK7 Catalyzes
Stereospecific Detoxification of Methylglyoxal
Consistent with Glyoxalase and Not Deglycase Function
por: Coukos, John S., et al.
Publicado: (2023) -
Glyoxalase I Gene Deletion Mutants of Leishmania donovani Exhibit Reduced Methylglyoxal Detoxification
por: Chauhan, Swati C., et al.
Publicado: (2009) -
Presence of unique glyoxalase III proteins in plants indicates the existence of shorter route for methylglyoxal detoxification
por: Ghosh, Ajit, et al.
Publicado: (2016) -
Listeria monocytogenes requires cellular respiration for NAD(+) regeneration and pathogenesis
por: Rivera-Lugo, Rafael, et al.
Publicado: (2022)