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Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2

The microtubule-associated protein tau is implicated in multiple degenerative diseases including retinal diseases such as glaucoma; however, the way tau initiates retinopathy is unclear. Previous retinal assessments in mouse models of tauopathy suggest that mutations in four-repeat (4R) tau are asso...

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Detalles Bibliográficos
Autores principales:	Ngolab, Jennifer, Canchi, Saranya, Rasool, Suhail, Elmaarouf, Abderrahman, Thomas, Kimberly, Sarsoza, Floyd, Grundman, Jennifer, Mante, Michael, Florio, Jazmin, Nandankar, Nimisha, Korouri, Shaina, Zago, Wagner, Masliah, Eliezer, Rissman, Robert A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373010/ https://www.ncbi.nlm.nih.gov/pubmed/33516874 http://dx.doi.org/10.1016/j.nbd.2021.105277

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