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noisyR: enhancing biological signal in sequencing datasets by characterizing random technical noise
High-throughput sequencing enables an unprecedented resolution in transcript quantification, at the cost of magnifying the impact of technical noise. The consistent reduction of random background noise to capture functionally meaningful biological signals is still challenging. Intrinsic sequencing v...
Autores principales: | Moutsopoulos, Ilias, Maischak, Lukas, Lauzikaite, Elze, Vasquez Urbina, Sergio A, Williams, Eleanor C, Drost, Hajk-Georg, Mohorianu, Irina I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373073/ https://www.ncbi.nlm.nih.gov/pubmed/34076236 http://dx.doi.org/10.1093/nar/gkab433 |
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