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Long-read whole-genome methylation patterning using enzymatic base conversion and nanopore sequencing

Long-read whole-genome sequencing analysis of DNA methylation would provide useful information on the chromosomal context of gene expression regulation. Here we describe the development of a method that improves the read length generated by using the bisulfite-sequencing-based approach. In this meth...

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Detalles Bibliográficos
Autores principales: Sakamoto, Yoshitaka, Zaha, Suzuko, Nagasawa, Satoi, Miyake, Shuhei, Kojima, Yasuyuki, Suzuki, Ayako, Suzuki, Yutaka, Seki, Masahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373077/
https://www.ncbi.nlm.nih.gov/pubmed/34019650
http://dx.doi.org/10.1093/nar/gkab397