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Long-read whole-genome methylation patterning using enzymatic base conversion and nanopore sequencing
Long-read whole-genome sequencing analysis of DNA methylation would provide useful information on the chromosomal context of gene expression regulation. Here we describe the development of a method that improves the read length generated by using the bisulfite-sequencing-based approach. In this meth...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373077/ https://www.ncbi.nlm.nih.gov/pubmed/34019650 http://dx.doi.org/10.1093/nar/gkab397 |