Discovering single nucleotide variants and indels from bulk and single-cell ATAC-seq

Genetic variants and de novo mutations in regulatory regions of the genome are typically discovered by whole-genome sequencing (WGS), however WGS is expensive and most WGS reads come from non-regulatory regions. The Assay for Transposase-Accessible Chromatin (ATAC-seq) generates reads from regulator...

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Detalles Bibliográficos
Autores principales: Massarat, Arya R, Sen, Arko, Jaureguy, Jeff, Tyndale, Sélène T, Fu, Yi, Erikson, Galina, McVicker, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373110/
https://www.ncbi.nlm.nih.gov/pubmed/34313779
http://dx.doi.org/10.1093/nar/gkab621

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